Read about how to find out if you're a carrier of thalassaemia and what it means for your health and any children you have.

If you're a carrier of thalassaemia it means you carry the faulty genes that cause thalassaemia, but you don't have any serious health problems yourself.

Being a carrier of the trait is sometimes known as having the thalassaemia trait or having "thalassaemia minor".

People who have the thalassaemia trait won't ever develop severe thalassaemia, but may be at risk of having a child with the condition and may sometimes experience mild anaemia.

You can find out if you're a carrier of thalassaemia by having a simple blood test.

This page covers:

Who can carry thalassaemia?

Testing for the thalassaemia trait

Advice about having children

Possible health problems

Carriers of other blood disorders

The NHS Sickle Cell and Thalassaemia Screening Programme also has detailed leaflets about being a beta thalassaemia carrier (PDF, 804kb) or a delta beta thalassaemia carrier (PDF, 779kb) that you might find useful.

Who can carry thalassaemia?

Anyone can be a carrier of thalassaemia, but it's much more common in people from certain ethnic backgrounds.

Thalassaemia mainly affects people who are from, or who have family members originally from:

  • around the Mediterranean – including Italy, Greece, and Cyprus
  • India, Pakistan and Bangladesh
  • the Middle East
  • China and Southeast Asia

You can have a blood test to see if you're a carrier if you think you may be at risk (see below).

Testing for the thalassaemia trait

Screening for thalassaemia is offered to all pregnant women in England. Read more about screening for thalassaemia in pregnancy.

Alternatively, anyone can ask to have a free test to find out if they're a carrier at any point. This can be particularly useful if:

  • you have a family history of thalassaemia or the thalassaemia trait
  • you're sexually active and want to find out if you're at risk of having a child with thalassaemia
  • your partner is known to have the thalassaemia trait

You can request the test from your GP surgery or nearest genetic counsellor will discuss the result and implications with you if you're found to have the trait.

Having children

If you have the thalassaemia trait, you're at risk of having children with thalassaemia, although this can only happen if your partner is also a carrier or has thalassaemia themselves.

If you're planning to have a child and you know you're a carrier, it's a good idea for your partner to be tested as well.

If you and your partner both have the trait for the main type of thalassaemia – beta thalassaemia – there's a:

  • 1 in 4 (25%) chance each child you have will not have thalassaemia or carry the thalassaemia trait
  • 1 in 2 (50%) chance each child you have will be a carrier of thalassaemia but won't have the condition themselves
  • 1 in 4 (25%) chance each child you have will be born with thalassaemia

If both of you are carriers and you're planning to have a baby, talk to your GP about getting a referral to a genetic counsellor who can explain the risks to your children and what your options are.

These include:

  • having tests during pregnancy to see if your baby is affected by thalassaemia major
  • adopting a child
  • trying in vitro fertilisation (IVF) with a donor egg or sperm
  • trying pre-implantation genetic diagnosis (PGD), although this isn't widely available in the UK

PGD is similar to IVF, but the resulting embryos are tested to check they don't have sickle cell disease before they're implanted in the womb. The Human Fertilisation and Embryology Authority (HFEA) has more information about PGD.

Possible health problems

You won't develop severe thalassaemia at any point if you're a carrier of the condition. You can live a normal life and won't experience any significant health problems as a result.

However, you may develop mild anaemia, which is where there are low levels of haemoglobin (a substance that transports oxygen) in the blood.

This can cause symptoms such as tiredness (fatigue) and pale skin, but may only be picked up with a blood test.

If you have anaemia, it's important not to take iron supplements for it unless you're diagnosed with iron deficiency anaemia. Taking iron supplements when you already have enough iron in your body could be harmful.

Carriers of other blood disorders

People who are carriers of thalassaemia are also at risk of having a child with a blood disorder if their partner is a carrier of a different type of blood disorder.

You can find more detailed information about some of the other types of carrier in the following leaflets:

Your Neighbourhood Professionals. Just a Click Away! B W Consultancy Natasha Mazzoni  Counselling & Therapy Sky Mitchell Counsellor
© Neighbourhood Direct Ltd 2018
121 Theobald Street, Borehamwood, Herts, WD6 4PT
  • Telephone 020 8953 3355
Practice Website supplied by Oldroyd Publishing Group
Your Neighbourhood Professionals. Just a Click Away! B W Consultancy Natasha Mazzoni  Counselling & Therapy Sky Mitchell Counsellor
Back to top